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A Small Dose of Solvents

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References / Additional Information (updated 10/26/04)

SOLVENT DOSSIER

Name: Solvent (broad class of chemicals)
Use: varied - recreational (alcohol) to industrial, gasoline
Source: synthetic chemistry, petroleum products; plant oils
Recommended daily intake: none (not essential)
Absorption: intestine, inhalation (major), skin
Sensitive individuals: fetus, children
Toxicity/symptoms: nervous system, reproductive system, and death,
General facts: long history of use (alcohol), highly volatile of solvent results in inhalation exposure of vapors
Environmental: volatile organic compounds react with sunlight to produce smog
Recommendations: avoid, proper workplace protection


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REFERENCES / ADDITIONAL INFORMATION

European, Asian, and International Agencies

United Nations Office for Drug Control and Crime Prevention (UN ODCCP). Online.(accessed: 9 April 2003).

North American Agencies

U.S. Department of Labor - Occupational Safety & Health Administration (OSHA). Online. (accessed: 9 April 2003).
This site has extensive information on solvents in the workplace.
U.S. Agency for Toxic Substance Disease Registry (ATSDR). Online. (accessed: 9 April 2003).
Site contains fact sheets and case studies on many common solvents.
U.S. National Institute on Drug Abuse (NIDA). Online. (accessed: 9 April 2003).
Site contains information in inhalants as drugs of abuse.
U.S. Environmental Protection Agency (EPA) Integrated Solvent Substitution Data System. Online. (accessed: 9 April 2003).
Site has comprehensive information on alternatives to solvents for products and processes.

Non-Government Organizations

The Wood Library-Museum of Anesthesiology. Online. (accessed: 9 April 2003).
The objective of the Wood Library-Museum of Anesthesiology is to collect and preserve literature and equipment pertaining to anesthesiology and to make available to the anesthesiology community, others in the medical profession and the public the most comprehensive educational, scientific and archival resources in anesthesiology
Anesthesia Nursing & Medicine. Online. (accessed: 9 April 2003).
Site has in-depth information on the history and current practice of anesthesia.

References

Charles Darwin The Autobiography of Charles Darwin 1809-1882. by Charles Darwin, Nora Barlow (Editor), W.W. Norton & Company, New York, NY, 1993, 253 pages.

MMWR (2001). n-Hexane--Related Peripheral Neuropathy Among Automotive Technicians -- California, 1999-2000. Vol 50, No 45;1011, 11/16/2001. Online. (accessed: 9 April 2003).

Dionne Laslo-Baker, MSc; Maru Barrera, PhD; Dafna Knittel-Keren, BSc; Eran Kozer, MD; Jacob Wolpin, PhD; Sohail Khattak, MD; Richard Hackman, MD; Joanne Rovet, PhD; Gideon Koren, MD, FABMT, FRCPC. Child Neurodevelopmental Outcome and Maternal Occupational Exposure to Solvents. Arch Pediatr Adolesc Med. 2004;158:956-961.

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